| Business | Phone |
| Friendship United Methodist 21 Friendship Church Rd, Nesmith 29580 | (843) 382-8317 |
| St John Holiness Church 125 Taylor Cir, Nesmith 29580 | (843) 558-4085 |
| Nesmith Baptist Church Po Box 123, Nesmith 29580 | (843) 382-2921 |
| Nesmith Baptist Church Study 2836 Nesmith Rd, Nesmith 29580 | (843) 382-2921 |
| Nesmith Way Of Cross Church 2774 Turkey Creek Rd, Nesmith 29580 | (843) 382-4619 |
| Nesmith Way Of Cross Church Rr 1, Nesmith 29580 | (843) 382-4619 |